Gluten/Coeliac Genetic Profile 2 Blood Test Marylebone
From 1 October 2026 — until then book at South Kensington or St Paul's. South Kensington · St Paul's
£410
+ £50 phlebotomy fee (per visit)
+ £50 phlebotomy (per visit)
Confidential Results
Secure online portal
Fast Results
10 days"
Professional Service
Experienced phlebotomists
Wimpole Street, Marylebone (opening 1 October 2026)
Opening hours from 1 October 2026
- Monday
- 9am – 6pm
- Tuesday
- 9am – 8pm
- Wednesday
- 9am – 6pm
- Thursday
- 9am – 8pm
- Friday
- 8am – 5pm
- Saturday
- 10am – 4pm
- Sunday
- Closed
- Bond Street — about 6 minutes (Central, Jubilee & Elizabeth lines)
- Oxford Circus — about 7 minutes (Central, Bakerloo & Victoria lines)
Wimpole Street, Marylebone
From 1 October 2026 the Gluten/Coeliac Genetic Profile 2 can be arranged at Wimpole Street Medical & Dental for £410. A venous blood sample (serum and EDTA) is taken by a nurse or phlebotomist and sent to a UKAS-accredited partner laboratory, which quotes 10 days for this coeliac disease and gluten test. The laboratory report shows each value for celiac Disease and HLA-DQ2 gene against its reference range and is released to your portal; we do not interpret results, so take it to your GP or a clinician.
Gluten/Coeliac Genetic Profile 2’s place in coeliac disease and gluten testing
- Sample
- venous blood sample (serum and EDTA)
- Laboratory turnaround
- 10 days
- Appointment
- 20 minutes
- Standard price
- £410 + £50 phlebotomy per visit
What Gluten/Coeliac Genetic Profile 2 measures
Laboratories file the Gluten/Coeliac Genetic Profile 2 under celiac Disease, HLA-DQ2 gene and HLA-DQ8 gene. The following sections set out how a coeliac disease and gluten test of this kind is measured and read.
Coeliac serology measures tissue transglutaminase IgA (tTG-IgA), the primary antibody produced when gluten damages the small bowel lining, alongside total IgA to make sure the test is valid; tTG-IgG and deamidated gliadin antibodies are used where IgA is low. HLA DQ2/DQ8 genotyping identifies whether you carry the genes that make coeliac disease possible — almost everyone with the condition has one of them, but so does a third of the general population. Gluten sensitivity profiles combine serology with genetics and nutritional markers.
Who considers Gluten/Coeliac Genetic Profile 2
- People often consider coeliac testing if they have bloating, loose stools, wind or abdominal pain that comes and goes.
- Unexplained iron, B12 or folate deficiency, or osteoporosis at a young age, are common prompts.
- A first-degree relative with coeliac disease raises the likelihood roughly tenfold and is a recognised reason to test.
- Those with type 1 diabetes or autoimmune thyroid disease frequently check, as the conditions cluster.
- An itchy blistering rash on the elbows, knees or buttocks may lead to testing for the skin form of the condition.
Preparing for your Gluten/Coeliac Genetic Profile 2
- 1Keep eating gluten — bread, pasta, cereals — daily for at least six weeks before the blood test; a gluten-free diet lowers the antibodies and can produce a false negative.
- 2No fasting is needed for serology or the HLA gene test.
- 3If you have already gone gluten-free and cannot face reintroducing it, the HLA test can still be useful, as a negative result makes coeliac disease very unlikely.
Sample for this test: venous blood sample (serum and EDTA).
Understanding your Gluten/Coeliac Genetic Profile 2 results
A clearly raised tTG-IgA, particularly at more than ten times the upper limit, can indicate coeliac disease with high probability; in adults, confirmation by small-bowel biopsy is still usually recommended before committing to a lifelong diet. A negative tTG with a normal total IgA makes active coeliac disease unlikely provided gluten was being eaten. A negative HLA DQ2/DQ8 result effectively excludes the condition, whereas a positive one only shows susceptibility.
Coeliac serology is only reliable while gluten is in the diet, and a result is interpreted alongside symptoms, nutritional markers and, where needed, biopsy.
Related areas of testing at Wimpole Street: food intolerance and digestive sensitivity, iron and ferritin, vitamin B12 and folate, autoimmune and immunology.
Pricing
Gluten/Coeliac Genetic Profile 2
Individual test
Phlebotomy Fee
Blood draw by qualified phlebotomist (per visit)
Total
£460Payment is collected at the clinic. The phlebotomy fee is charged once per visit, regardless of the number of tests booked.
From booking the Gluten/Coeliac Genetic Profile 2 to reading your result
- 1
Choose your test
Select the Gluten/Coeliac Genetic Profile 2 and any others you want run from the same visit. Until 1 October 2026 the identical test can be booked at South Kensington or St Paul’s.
- 2
Nurse-led sample
From 1 October 2026 the venous blood sample (serum and EDTA) is taken at 22 Wimpole Street, Marylebone by our nursing team, led by Precious Agbonmamwen, Registered Adult Nurse (NMC 20H1641E). Identity is checked and any preparation questions answered first.
- 3
UKAS-accredited laboratory
The sample travels to a UKAS-accredited partner laboratory, whose methods and reference ranges match those used across the NHS and private sectors.
- 4
Laboratory report to your secure portal
The laboratory report is released to your secure portal — typically from 24 hours; the laboratory quotes 10 days for this test. It shows each value against the reference range and flags anything outside it; discuss the report with your GP or a clinician.
Why test at Wimpole Street
Wimpole Street Medical & Dental opens at 22 Wimpole Street on 1 October 2026. Medical services are for patients aged 16 and over; registration with the CQC is in progress ahead of opening.
Wimpole Street, Marylebone (opening 1 October 2026)
- Bond Street — about 6 minutes (Central, Jubilee & Elizabeth lines)
- Oxford Circus — about 7 minutes (Central, Bakerloo & Victoria lines)
- Registration with the CQC is in progress ahead of opening; our South Kensington and St Paul’s clinics are CQC registered.
- Self-referral: you choose the test and book directly — no GP referral is needed, and the laboratory report is yours to take to your GP or a clinician.
- The same catalogue already runs at South Kensington and St Paul’s, so you can test now and move your records to Marylebone later.
Other tests often considered alongside Gluten/Coeliac Genetic Profile 2
- Tissue Transglutaminase IgGWimpole Street, Marylebone · from 1 October 2026
- Gliadin Antibodies (IgG) (deamidated) (Venous)Wimpole Street, Marylebone · from 1 October 2026
- Tissue Transglutaminase IgA (Coeliac) (Venous)**Wimpole Street, Marylebone · from 1 October 2026
- Coeliac/Gluten Sensitivity ProfileWimpole Street, Marylebone · from 1 October 2026
- HLA Tissue Typing Coeliac Disease – DQ2/DQ8Wimpole Street, Marylebone · from 1 October 2026
- Coeliac/Gluten Genetic Profile 2Wimpole Street, Marylebone · from 1 October 2026
Frequently Asked Questions
A venous blood sample (serum and EDTA). A nurse or phlebotomist collects it at 22 Wimpole Street, Marylebone from 1 October 2026; the appointment allows time for identity checks and any preparation questions. The laboratory quotes 10 days for this test.
Ready to Book Your Test?
Wimpole Street opens 1 October 2026. Register your interest for the Marylebone diary, or book the same test now at South Kensington or St Paul's.
Important information about the Gluten/Coeliac Genetic Profile 2 at Wimpole Street
- Medical services at Wimpole Street Medical & Dental are for patients aged 16 and over.
- This is a self-referral service: you choose the test and book directly — no GP referral is needed.
- Nurse-led by Precious Agbonmamwen, Registered Adult Nurse (NMC 20H1641E), who oversees sample-taking standards, infection control and the patient pathway. The nursing team does not interpret results.
- A laboratory result is not a diagnosis and this page is not a substitute for medical advice. We do not provide clinical interpretation of results — please discuss your report with your GP or a clinician, particularly if a value is flagged or you have symptoms.
- CQC registration for Wimpole Street is in progress ahead of the opening on 1 October 2026; our South Kensington and St Paul’s clinics are CQC registered.
- Your results are held on a secure portal and treated as strictly confidential, except where disclosure is required by law.
- If you are seriously unwell, call 999. For urgent advice that is not an emergency, call NHS 111.
