HRT Profile 2 Blood Test Marylebone
From 1 October 2026 — until then book at South Kensington or St Paul's. South Kensington · St Paul's
£197
+ £50 phlebotomy fee (per visit)
+ £50 phlebotomy (per visit)
Confidential Results
Secure online portal
Fast Results
1 day"
Professional Service
Experienced phlebotomists
Wimpole Street, Marylebone (opening 1 October 2026)
Opening hours from 1 October 2026
- Monday
- 9am – 6pm
- Tuesday
- 9am – 8pm
- Wednesday
- 9am – 6pm
- Thursday
- 9am – 8pm
- Friday
- 8am – 5pm
- Saturday
- 10am – 4pm
- Sunday
- Closed
- Bond Street — about 6 minutes (Central, Jubilee & Elizabeth lines)
- Oxford Circus — about 7 minutes (Central, Bakerloo & Victoria lines)
Wimpole Street, Marylebone
From 1 October 2026 the HRT Profile 2 can be arranged at Wimpole Street Medical & Dental for £197. A venous blood sample (serum and fluoride oxalate) is taken by a nurse or phlebotomist and sent to a UKAS-accredited partner laboratory, which quotes 1 day for this menopause and perimenopause test. The laboratory report shows each value for hormone Replacement Therapy and estrogen Levels against its reference range and is released to your portal; we do not interpret results, so take it to your GP or a clinician.
HRT Profile 2’s place in menopause and perimenopause testing
- Sample
- venous blood sample (serum and fluoride oxalate)
- Laboratory turnaround
- 1 day
- Appointment
- 20 minutes
- Standard price
- £197 + £50 phlebotomy per visit
What HRT Profile 2 measures
HRT Profile 2 is most often requested in connection with hormone Replacement Therapy, estrogen Levels and progesterone Levels, which is why it sits within the menopause and perimenopause group at Wimpole Street.
Menopause profiles measure FSH, LH and oestradiol, which shift as ovarian activity declines, often alongside thyroid function because the symptoms overlap. HRT profiles check oestradiol, and sometimes testosterone and SHBG, in women already using hormone therapy to see whether absorption is adequate. Bone markers and lipids are sometimes added because oestrogen loss affects both.
Preparing for your HRT Profile 2
- 1If you are still having periods, a day 2 to 5 sample gives the most interpretable FSH; if cycles are erratic, any day is acceptable and a repeat six weeks later can help.
- 2Combined hormonal contraception suppresses FSH and makes the test uninformative; discuss timing with the nurse.
- 3For HRT monitoring, take your usual dose and note when you last applied gel or a patch.
Sample for this test: venous blood sample (serum and fluoride oxalate).
Who considers HRT Profile 2
- People often consider these tests if hot flushes, night sweats or disrupted sleep have appeared alongside changes in their periods.
- Women under 45 with menopausal symptoms are commonly advised to test, as guidelines suggest blood tests are most useful in this group.
- Those using transdermal HRT who still have symptoms may check oestradiol to see whether the dose is being absorbed.
- Brain fog, anxiety or joint aches without another explanation sometimes lead to a hormone and thyroid check.
- Women who have had a hysterectomy but kept their ovaries may want to know where they are in the transition.
Understanding your HRT Profile 2 results
A persistently raised FSH with low oestradiol can indicate the ovaries are winding down, but a single reading in perimenopause can swing from menopausal to premenopausal within weeks, which is why repeat testing is common. In women over 45 with typical symptoms, national guidance does not require blood tests at all, and results are used mainly to exclude other causes. On HRT, a low oestradiol despite treatment may suggest poor absorption rather than an inadequate prescription.
Perimenopausal hormones fluctuate markedly, so a normal result does not exclude the transition and an abnormal one is not a diagnosis without the clinical picture.
Related areas of testing at Wimpole Street: female hormones and fertility, thyroid function, bone, calcium and parathyroid, cholesterol and lipids.
Pricing
HRT Profile 2
Individual test
Phlebotomy Fee
Blood draw by qualified phlebotomist (per visit)
Total
£247Payment is collected at the clinic. The phlebotomy fee is charged once per visit, regardless of the number of tests booked.
From booking the HRT Profile 2 to reading your result
- 1
Choose your test
Select the HRT Profile 2 and any others you want run from the same visit. Until 1 October 2026 the identical test can be booked at South Kensington or St Paul’s.
- 2
Nurse-led sample
From 1 October 2026 the venous blood sample (serum and fluoride oxalate) is taken at 22 Wimpole Street, Marylebone by our nursing team, led by Precious Agbonmamwen, Registered Adult Nurse (NMC 20H1641E). Identity is checked and any preparation questions answered first.
- 3
UKAS-accredited laboratory
The sample travels to a UKAS-accredited partner laboratory, whose methods and reference ranges match those used across the NHS and private sectors.
- 4
Laboratory report to your secure portal
The laboratory report is released to your secure portal — typically from 24 hours; the laboratory quotes 1 day for this test. It shows each value against the reference range and flags anything outside it; discuss the report with your GP or a clinician.
Why test at Wimpole Street
Wimpole Street Medical & Dental opens at 22 Wimpole Street on 1 October 2026. Medical services are for patients aged 16 and over; registration with the CQC is in progress ahead of opening.
Wimpole Street, Marylebone (opening 1 October 2026)
- Bond Street — about 6 minutes (Central, Jubilee & Elizabeth lines)
- Oxford Circus — about 7 minutes (Central, Bakerloo & Victoria lines)
- Self-referral: you choose the test and book directly — no GP referral is needed, and the laboratory report is yours to take to your GP or a clinician.
- Bond Street is about six minutes on foot and Oxford Circus about seven, so the clinic suits people working across the West End.
- The same catalogue already runs at South Kensington and St Paul’s, so you can test now and move your records to Marylebone later.
Other tests often considered alongside HRT Profile 2
Frequently Asked Questions
A venous blood sample (serum and fluoride oxalate). A nurse or phlebotomist collects it at 22 Wimpole Street, Marylebone from 1 October 2026; the appointment allows time for identity checks and any preparation questions. The laboratory quotes 1 day for this test.
Ready to Book Your Test?
Wimpole Street opens 1 October 2026. Register your interest for the Marylebone diary, or book the same test now at South Kensington or St Paul's.
Important information about the HRT Profile 2 at Wimpole Street
- Medical services at Wimpole Street Medical & Dental are for patients aged 16 and over.
- This is a self-referral service: you choose the test and book directly — no GP referral is needed.
- Nurse-led by Precious Agbonmamwen, Registered Adult Nurse (NMC 20H1641E), who oversees sample-taking standards, infection control and the patient pathway. The nursing team does not interpret results.
- A laboratory result is not a diagnosis and this page is not a substitute for medical advice. We do not provide clinical interpretation of results — please discuss your report with your GP or a clinician, particularly if a value is flagged or you have symptoms.
- CQC registration for Wimpole Street is in progress ahead of the opening on 1 October 2026; our South Kensington and St Paul’s clinics are CQC registered.
- Your results are held on a secure portal and treated as strictly confidential, except where disclosure is required by law.
- If you are seriously unwell, call 999. For urgent advice that is not an emergency, call NHS 111.
