Methylmalonic Acid – Urine Blood Test Marylebone
From 1 October 2026 — until then book at South Kensington or St Paul's. South Kensington · St Paul's
£167
Confidential Results
Secure online portal
Fast Results
2 weeks"
Professional Service
Experienced phlebotomists
Wimpole Street, Marylebone (opening 1 October 2026)
Opening hours from 1 October 2026
- Monday
- 9am – 6pm
- Tuesday
- 9am – 8pm
- Wednesday
- 9am – 6pm
- Thursday
- 9am – 8pm
- Friday
- 8am – 5pm
- Saturday
- 10am – 4pm
- Sunday
- Closed
- Bond Street — about 6 minutes (Central, Jubilee & Elizabeth lines)
- Oxford Circus — about 7 minutes (Central, Bakerloo & Victoria lines)
Wimpole Street, Marylebone
Within the vitamin B12 and folate range at Wimpole Street, the Methylmalonic Acid – Urine is the test to consider when the question concerns vitamin B12 deficiency, kidney function and metabolic disorders. It costs £167, and once the Marylebone clinic opens on 1 October 2026 a nurse or phlebotomist takes the catheter urine sample, with the laboratory typically reporting in 2 weeks. Medical services are for patients aged 16 and over, self-referral with no GP referral needed, and the laboratory report is delivered to your secure portal.
Methylmalonic Acid – Urine’s place in vitamin B12 and folate testing
- Sample
- catheter urine sample
- Laboratory turnaround
- 2 weeks
- Appointment
- 20 minutes
- Standard price
- £167
What Methylmalonic Acid – Urine measures
Methylmalonic Acid – Urine is most often requested in connection with vitamin B12 deficiency, kidney function and metabolic disorders, which is why it sits within the vitamin B12 and folate group at Wimpole Street.
These tests measure the two vitamins most closely tied to red blood cell production and nerve function. Total B12 reports everything circulating in the blood, whereas active B12 (holotranscobalamin) measures the fraction cells can use; folate can be measured in serum for recent intake or in red cells for a longer-term average. Methylmalonic acid and intrinsic factor antibodies are add-on tests that help to explain why B12 might be low.
Preparing for your Methylmalonic Acid – Urine
- 1Fasting is not required for B12 or folate, though a morning appointment keeps conditions similar between repeat tests.
- 2If you have recently had a B12 injection or a high-dose oral supplement, tell the nurse; levels can read high for weeks afterwards.
- 3Biotin in large doses can interfere with some immunoassays; pausing it for two days is a sensible precaution.
Sample for this test: catheter urine sample.
Who considers Methylmalonic Acid – Urine
- People often consider this test if they follow a vegan or largely plant-based diet, because B12 comes almost entirely from animal sources.
- Pins and needles, numbness, poor balance or memory changes are symptoms that commonly prompt a check.
- Anyone taking metformin or long-term acid-suppressing medication may want to know their level, as both can reduce absorption.
- A full blood count showing large red cells (a high MCV) frequently leads to B12 and folate being measured next.
- Those with coeliac disease, Crohn’s disease or previous stomach surgery often monitor B12 periodically.
Understanding your Methylmalonic Acid – Urine results
A low B12 or folate can indicate dietary shortfall, poor absorption or, less commonly, an autoimmune cause such as pernicious anaemia. Values in the grey zone between clearly low and clearly adequate are common, and active B12 or methylmalonic acid may help to decide whether cells are actually short of the vitamin. High readings are usually explained by supplements and are rarely a concern on their own.
B12 and folate results are read together with your full blood count, symptoms and diet, and a normal serum level does not entirely exclude a functional deficiency.
Related areas of testing at Wimpole Street: full blood count, iron and ferritin, nutrition, vitamins and trace elements, coeliac disease and gluten.
Pricing
Methylmalonic Acid – Urine
Individual test
Total
£167Payment is collected at the clinic. The phlebotomy fee is charged once per visit, regardless of the number of tests booked.
From booking the Methylmalonic Acid – Urine to reading your result
- 1
Choose your test
Select the Methylmalonic Acid – Urine and any others you want run from the same visit. Until 1 October 2026 the identical test can be booked at South Kensington or St Paul’s.
- 2
Nurse-led sample
From 1 October 2026 the catheter urine sample is taken at 22 Wimpole Street, Marylebone by our nursing team, led by Precious Agbonmamwen, Registered Adult Nurse (NMC 20H1641E). Identity is checked and any preparation questions answered first.
- 3
UKAS-accredited laboratory
The sample travels to a UKAS-accredited partner laboratory, whose methods and reference ranges match those used across the NHS and private sectors.
- 4
Laboratory report to your secure portal
The laboratory report is released to your secure portal — typically from 24 hours; the laboratory quotes 2 weeks for this test. It shows each value against the reference range and flags anything outside it; discuss the report with your GP or a clinician.
Why test at Wimpole Street
Wimpole Street Medical & Dental opens at 22 Wimpole Street on 1 October 2026. Medical services are for patients aged 16 and over; registration with the CQC is in progress ahead of opening.
Wimpole Street, Marylebone (opening 1 October 2026)
- Bond Street — about 6 minutes (Central, Jubilee & Elizabeth lines)
- Oxford Circus — about 7 minutes (Central, Bakerloo & Victoria lines)
- One standard price applies to everyone — there is no members’ tier at Wimpole Street.
- Evening appointments until 8pm on Tuesday and Thursday, and Saturday opening, are planned from day one.
- Registration with the CQC is in progress ahead of opening; our South Kensington and St Paul’s clinics are CQC registered.
Other tests often considered alongside Methylmalonic Acid – Urine
- Vitamin B9 (Folic acid) – Red cellWimpole Street, Marylebone · from 1 October 2026
- Vitamin B9 (Folic acid) – SerumWimpole Street, Marylebone · from 1 October 2026
- Folate (Red Cell)Wimpole Street, Marylebone · from 1 October 2026
- Folate (Serum)Wimpole Street, Marylebone · from 1 October 2026
- Gastric Parietal AutoantibodiesWimpole Street, Marylebone · from 1 October 2026
Frequently Asked Questions
A catheter urine sample. A nurse or phlebotomist collects it at 22 Wimpole Street, Marylebone from 1 October 2026; the appointment allows time for identity checks and any preparation questions. The laboratory quotes 2 weeks for this test.
Ready to Book Your Test?
Wimpole Street opens 1 October 2026. Register your interest for the Marylebone diary, or book the same test now at South Kensington or St Paul's.
Important information about the Methylmalonic Acid – Urine at Wimpole Street
- Medical services at Wimpole Street Medical & Dental are for patients aged 16 and over.
- This is a self-referral service: you choose the test and book directly — no GP referral is needed.
- Nurse-led by Precious Agbonmamwen, Registered Adult Nurse (NMC 20H1641E), who oversees sample-taking standards, infection control and the patient pathway. The nursing team does not interpret results.
- A laboratory result is not a diagnosis and this page is not a substitute for medical advice. We do not provide clinical interpretation of results — please discuss your report with your GP or a clinician, particularly if a value is flagged or you have symptoms.
- CQC registration for Wimpole Street is in progress ahead of the opening on 1 October 2026; our South Kensington and St Paul’s clinics are CQC registered.
- Your results are held on a secure portal and treated as strictly confidential, except where disclosure is required by law.
- If you are seriously unwell, call 999. For urgent advice that is not an emergency, call NHS 111.
