Macrolide Resistance Test (Mgen) — Marylebone
Strictly confidential Macrolide Resistance Test (Mgen) at Wimpole Street Medical & Dental, 22 Wimpole Street, from 1 October 2026. Nurse-taken sample, UKAS-accredited laboratory, results via secure portal.
From 1 October 2026 — until then book at South Kensington or St Paul's.
Price
£230
All-inclusive price
- Results within 1-2 weeks"
- Confidential service
- No GP referral needed
- Professional clinical environment
- Results via secure portal
- Nurse-led expert care
Wimpole Street, Marylebone (opening 1 October 2026)
Opening hours from 1 October 2026
- Monday
- 9am – 6pm
- Tuesday
- 9am – 8pm
- Wednesday
- 9am – 6pm
- Thursday
- 9am – 8pm
- Friday
- 8am – 5pm
- Saturday
- 10am – 4pm
- Sunday
- Closed
- Bond Street — about 6 minutes (Central, Jubilee & Elizabeth lines)
- Oxford Circus — about 7 minutes (Central, Bakerloo & Victoria lines)
Wimpole Street, Marylebone
From 1 October 2026 the Macrolide Resistance Test (Mgen) is available at Wimpole Street Medical & Dental for £230, one standard price with no members’ tier. A swab for PCR and first-catch urine sample is collected by a nurse and analysed by a UKAS-accredited partner laboratory, which quotes 1-2 weeks. The laboratory report states the result for antibiotic Resistance and mycoplasma genitalium clearly and is released only to you through a secure portal; we do not interpret it, so discuss any positive with a sexual health clinician or your GP.
Macrolide Resistance Test (Mgen)’s place in mycoplasma, ureaplasma and trichomonas testing
- Sample
- swab for PCR and first-catch urine sample
- Laboratory turnaround
- 1-2 weeks
- Appointment
- 20 minutes
- Standard price
- £230
What Macrolide Resistance Test (Mgen) measures
Laboratories file the Macrolide Resistance Test (Mgen) under antibiotic Resistance, mycoplasma genitalium and STD Diagnosis. The following sections set out how a mycoplasma, ureaplasma and trichomonas test of this kind is measured and read.
These infections are detected by PCR on a first-catch urine sample or a vaginal, urethral or rectal swab. Mycoplasma genitalium is a bacterium increasingly recognised as a cause of urethritis and pelvic inflammatory disease, and because antibiotic resistance is common, a positive result is usually followed by a macrolide resistance test that guides which drug to use. Ureaplasma is often part of normal flora and is tested mainly where symptoms persist without another cause, while Trichomonas vaginalis is a parasite that causes discharge and irritation and is readily detected by PCR.
Preparing for your Macrolide Resistance Test (Mgen)
- 1Hold urine for at least an hour before providing a first-catch sample.
- 2Avoid vaginal creams, pessaries or douching for 48 hours before a swab.
- 3Two weeks after exposure is a sensible minimum interval, as with other bacterial STIs.
- 4Mention any antibiotics taken in the previous month, particularly azithromycin or doxycycline, which can affect results and resistance patterns.
Sample for this test: swab for PCR and first-catch urine sample.
Who considers Macrolide Resistance Test (Mgen)
- People often consider these tests if they have urethral discharge or discomfort passing urine but a chlamydia and gonorrhoea test was negative.
- Frothy or fishy-smelling discharge with itching is a common prompt for trichomonas testing.
- Persistent or recurrent pelvic pain after standard STI treatment may lead to mycoplasma testing.
- A partner diagnosed with Mycoplasma genitalium or trichomonas is a clear reason to test.
- Some full STI profiles include these organisms as standard, others as an add-on.
Understanding your Macrolide Resistance Test (Mgen) results
A positive Mycoplasma genitalium result indicates infection that should be treated, and the resistance result determines whether a macrolide or an alternative is appropriate; partners should be tested. A positive trichomonas result is treated with a short antibiotic course for both partners. Ureaplasma is detected in many healthy people, so a positive result is interpreted cautiously and treated only where symptoms persist and other causes have been excluded.
Detection of these organisms does not always mean disease — particularly for ureaplasma — and treatment decisions should follow BASHH guidance with a sexual health clinician.
Severe pelvic pain with fever, or testicular pain and swelling, may indicate a complicated infection and should be assessed the same day via NHS 111 or a sexual health service.
Related areas of testing at Wimpole Street: chlamydia and gonorrhoea, STI screening profiles, sexual health, urine tests.
Pricing
Payment is collected at the clinic. No additional fees apply for this test.
From booking the Macrolide Resistance Test (Mgen) to reading your result
- 1
Choose your test
Select the Macrolide Resistance Test (Mgen) and any others you want run from the same visit. Until 1 October 2026 the identical test can be booked at South Kensington or St Paul’s.
- 2
Nurse-led sample
From 1 October 2026 the swab for PCR and first-catch urine sample is taken at 22 Wimpole Street, Marylebone by our nursing team, led by Precious Agbonmamwen, Registered Adult Nurse (NMC 20H1641E). Identity is checked and any preparation questions answered first.
- 3
UKAS-accredited laboratory
The sample travels to a UKAS-accredited partner laboratory, whose methods and reference ranges match those used across the NHS and private sectors.
- 4
Laboratory report to your secure portal
The laboratory report is released to your secure portal — typically from 24 hours; the laboratory quotes 1-2 weeks for this test. It shows each value against the reference range and flags anything outside it; discuss the report with your GP or a clinician.
Why test at Wimpole Street
Wimpole Street Medical & Dental opens at 22 Wimpole Street on 1 October 2026. Medical services are for patients aged 16 and over; registration with the CQC is in progress ahead of opening.
Wimpole Street, Marylebone (opening 1 October 2026)
- Bond Street — about 6 minutes (Central, Jubilee & Elizabeth lines)
- Oxford Circus — about 7 minutes (Central, Bakerloo & Victoria lines)
- Appointments at 22 Wimpole Street, Marylebone are booked under your name only; nothing is shared with a GP or insurer unless you ask, except where required by law.
- The same test is already available at South Kensington and St Paul’s if you have a concern before the Marylebone opening.
- Self-referral with no GP referral needed; the laboratory report is released only to you, and a positive result can be taken to a sexual health service for treatment.
Frequently Asked Questions
A swab for PCR and first-catch urine sample. A nurse or phlebotomist collects it at 22 Wimpole Street, Marylebone from 1 October 2026; the appointment allows time for identity checks and any preparation questions. The laboratory quotes 1-2 weeks for this test.
Other tests often considered alongside Macrolide Resistance Test (Mgen)
- Chlamydia/Gonorrhoea/Trichomonas – UrineWimpole Street, Marylebone · from 1 October 2026
- Mycoplasma genitalium/Ureaplasma by PCRWimpole Street, Marylebone · from 1 October 2026
- Chlamydia/Gonorrhoea/Trichomonas – PCR SwabWimpole Street, Marylebone · from 1 October 2026
- Mycoplasma genitalium Resistance – Urine or Vaginal (Self-collect)Wimpole Street, Marylebone · from 1 October 2026
- Ureaplasma urealyticum by PCRWimpole Street, Marylebone · from 1 October 2026
Ready to Get Tested?
Wimpole Street opens 1 October 2026. Register your interest, or book the same strictly confidential test now at South Kensington or St Paul's.
Important information about the Macrolide Resistance Test (Mgen) at Wimpole Street
- Medical services at Wimpole Street Medical & Dental are for patients aged 16 and over.
- This is a self-referral service: you choose the test and book directly — no GP referral is needed.
- Nurse-led by Precious Agbonmamwen, Registered Adult Nurse (NMC 20H1641E), who oversees sample-taking standards, infection control and the patient pathway. The nursing team does not interpret results.
- A laboratory result is not a diagnosis and this page is not a substitute for medical advice. We do not provide clinical interpretation of results — please discuss your report with your GP or a clinician, particularly if a value is flagged or you have symptoms.
- CQC registration for Wimpole Street is in progress ahead of the opening on 1 October 2026; our South Kensington and St Paul’s clinics are CQC registered.
- Your results are held on a secure portal and treated as strictly confidential, except where disclosure is required by law.
- If you are seriously unwell, call 999. For urgent advice that is not an emergency, call NHS 111.
